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Table2. : Estimated tissue concentrations in human populations exposed to dioxin and dioxin-like compounds

Study Population (date of exposure) Exposure Circumstance Primary Exposure No. of Samples Serum Level at Time of Study (pg/g lipid) Estimated serum concentration at lastexposure (pg/g lipid) Estimated body burden at last exposure (ng/kg.bw)1
* randomly selected 
Yusho(1968) Japan: Ingestion of contaminated rice oil PCBs PCDFs PCQs PCTs   Adipose tissue wet weight within 1 year of end of exposure. 2.8 mg/kg PCBs, 5.7 mg 2,3,4,7,8 PeCDF, 1.7µmg Hx total NA 600 mg PCBs 3.5 mg PCDFs (60 kg bw)
Yucheng (1979) Taiwan: Ingestion of contaminated rice oil PCBs PCDFs PCQs PCTs   Lipid adjusted serum within 1 year of end of exposure 60 mg/kg total PCB (range 4-188) 0.14µ mg/kg PCDF (range 0-0.27) NA Total ingested dose: 1000 mg PCBs 3.8 mg PCDFs
Seveso(1976) TCP reactor release TCDD 1976 Zone A: 296 Zone Bmax:80 Zone R: 48 1992 Zone A:6 Zone B*: 52 Zone R: 52 1976 Zone A: ND-56,000 (median=450) Zone B: ND -1450 (median=126) Zone R: ND-100 (median= 50) 1992 Zone A: 61.5 (mean) 71.5 (median) Zone B: 16.8 (mean) 12.5 (median) Zone R: 5.3 (median) 5.5 (median) Zone A: 333.8 388.7 Zone B: 111.4 77.6 67 78 22 16
Industrial Cohorts            
NIOSH TCP production TCDD 253 ND-3300 median: 90mean: 220 ND-32,000 median: 2,000 ND-6400 median: 400
Netherlands     48 geom. mean 22.9 (production) 87.2 (accident) geom. Mean286 (17-1160)1434 (301-3683) geom.mean 57 (3-232)287 (60-737)
BASF     138 15.4 (geom) 84.1(median): 5 yrs after end of experiment approx. 400 approx. 80
Boehringer
-Ingelheim
    48 48.9 (median):11yrs after end of experiment 141 (3-2252) 28 (1-450)
U.S. Air Force Ranch Hand Aerial spraying of Agent Orange in Vietnam TCDD   ND-800 median: 12.4 approx. 50 approx. 10
General population (Germany, 1996) Background PCDD PCDF 139 mean: 16.1 median: 15.2 Lowest: 7.3 95% 26.7 NA range: 1.5-5 ng (I)TEQ/kg.bw
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Table2. : Estimated tissue concentrations in human populations exposed to dioxin and dioxin-like compounds

Table 7: Estimated daily dietary intake of PCBs in the USA. a

JECFA ASSESSMENT

Dioxin Body Burden

Toxic Equivalents Scheme (TEFs & TEQs)

Daily Dioxin IntakesSome average daily intakes for long term exposures to dioxins:

Mass (weight) Units