Lowest Observed Adverse Effect Level
Similar term(s): LOAEL, LOAL (lowest observed effect level).
Definition:
The lowest tested dose of a substance that has been reported to cause harmful (adverse) health effects on people or animals.
More:
Can apply to a particular study, species (e.g. rat, dog), or all studies on a particular substance. The difference between LOAEL and LOEL rests on the definition of adverse effect only, that is, an experimental study that produced a LOAEL will have stated the adverse effect to be observed before initiation.
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