In biology, an adduct is a complex that forms when a chemical binds to a
biological molecule, such as DNA or protein.
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DNA adducts are altered forms of DNA that occur as the result of exposure to
carcinogens (in the case of smokers these would be the carcinogens present in
cigarette smoke). A DNA adduct, once formed, can be repaired, resulting in a
return to the original DNA structure or be mis-repaired, resulting in a
mutation. Protein adducts do not have adverse biological effects but can be used
as a measure of exposure to a foreign substance.
