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Exposure to mixture (“cocktails”) of chemical substances: Are the health and environmental risks adequately evaluated?

 

Glossary over Exposure to mixture (“cocktails”) of chemical substances:

Adverse health effect

A change in body function or cell structure that might lead to disease or health problems. (Source: ATSDR Glossary of Terms  )

Antagonistic effect

A biologic response to exposure to multiple substances that is less than would be expected if the known effects of the individual substances were added together. (Source: ATSDR Glossary of Terms  )

Endocrine system

A network of glands distributed throughout the body forms the endocrine system. These glands produce hormones that are released into the circulation and distributed to distant target sites via the blood. Hormones produced by these glands act as chemical messengers to control body functions such as growth, metabolism, sexual development, and egg and sperm production. (Source: EMCOM Glossary  )

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Metabolite

A substance that is the product of biological changes to a chemical. (Source: US EPA Glossary  )

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Nutrients

The approximately 20 chemical elements known to be essential for the growth of living organisms, including nitrogen, sulfur, phosphorus, and carbon. (Source: Millennium Ecosystem Assessment Glossary   )

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Pesticide

A toxic chemical product that kills harmful organisms (e.g., insecticides, fungicide, weedicides, rodenticides, acaricides). (Source: FAO Glossary of biotechnology & genetic engineering  )

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Physiology

Study of the biological, chemical and physical activities and processes that underlie the functioning of living organisms (cells, tissues, organs, and organ systems) and their parts. (Source: GreenFacts)

Risk assessment

A scientifically based process consisting of four steps:

  • hazard identification,
  • hazard characterization,
  • exposure assessment and
  • risk characterization
(Source:   Official Journal of the European Communities 2002 L 31 )

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Scientific Committee on Consumer Safety

The SCCS provides opinions on questions concerning all types of health and safety risks (notably chemical, biological, mechanical and other physical risks) of non-food consumer products (for example: cosmetic products and their ingredients, toys, textiles, clothing, personal care and household products such as detergents, etc.) and services (for example: tattooing, artificial sun tanning, etc.). For further information on the SCCS, see:

http://ec.europa.eu/health/scientific_committees/consumer_safety/index_en.htm 

Scientific Committee on Emerging and Newly Identified Health Risks

The Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) was set up in 2004 by the European Commission to provide the Commission with unambiguous scientific advice on the safety of a series of issues requiring a comprehensive assessment of the risks, such as new technologies, medical devices, etc.

The SCENIHR advice is intended to enable risk managers to take the adequate and required actions in order to guarantee consumer safety or public health.

The SCENIHR addresses questions concerning emerging or newly-identified risks and on broad, complex or multi-disciplinary issues requiring a comprehensive assessment of risks to consumer safety or public health and related issues not covered by other Community risk- assessment bodies.

The Scientific Committee on Emerging and Newly Identified Health Risks is composed of a maximum of 13 members, but for any specific question may enlist the support of up to six associated members selected on the basis of their expertise. There is also a reserve list made up of candidates found suitable for a position in a Scientific Committee but not appointed. The members of the SCENIHR are appointed on the basis of their skills and experience in the fields in question, and consistent with this a geographical distribution that reflects the diversity of scientific problems and approaches in the European Union (EU). The experts' term of office is three years and is renewable for a maximum of three consecutive times. In agreement with the Commission, the Scientific Committees may turn to specialised external experts.

The SCENIHR complies with the principles of independence, transparency and confidentiality. The members therefore make a declaration of commitment to act in the public interest and a declaration of interests; requests for opinions, agendas, minutes and opinions are published; work and publications are done with regard to the need for commercial confidentiality. (Source: SCENIHR pages  )

Scientific Committee on Health and Environmental Risks

The Scientific Committee on Health and Environmental Risks (SCHER) is one of three independent non-food scientific committees that advise the European Commission on matters of consumer safety, public health and the environment.

The committee was set up in 2004 to provide the European Commission with scientific advice on health and environmental risks. It replaced the Scientific Committee on Toxicity, Ecotoxicity and the Environment (CSTEE).

SCHER addresses questions relating to examinations of the toxicity and ecotoxicity of chemicals, biochemicals and biological compound whose use may have harmful consequences for human health and the environment.

In particular, the Committee addresses questions related to new and existing chemicals, the restriction and marketing of dangerous substances, biocides, waste, environmental contaminants, plastic and other materials used for water pipe work (e.g. new organics substances), drinking water, indoor and ambient air quality. It addresses questions relating to human exposure to mixtures of chemicals, sensitisation and identification of endocrine disrupters.

The SCHER complies with the principles of independence, transparency and confidentiality. SCHER members therefore make a declaration of commitment to act in the public interest and a declaration of interests; requests for opinions, agendas, minutes and opinions are published; work and publications are done with regard to the need for commercial confidentiality.

For further information on the SCHER see:
SCHER website 

Synergy

When the combined effect of several forces operating is greater than the sum of the separate effects of the forces. (Source: Millennium Ecosystem Assessment  Glossary )

Taxonomy

The classification, especially of plants and animal, on the basis of differences and similarities between them. (Source: Illinois Wetlands Terms )

Toxicology

The study of the harmful effects of substances on humans or animals. (Source: ATSDR Glossary of Terms  )


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