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Home » DINP-DIDP » Level 3 » Question 7

Phthalate Di-isodecyl & Di-isononyl phthalates

7. Is further research needed?

    The source document for this Digest states:

    DIDP

    RESULTS

    ENVIRONMENT

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    The production and use of DIDP in PVC, other polymers, paints, sealing compounds and textile inks is unlikely to pose a risk to the environment. In addition, risks to the function of sewage treatment plants and the atmosphere are expected to be very low for both production and all uses.

    HUMAN HEALTH

    Human health (toxicity)

    Workers

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    The production and use of DIDP in PVC, other polymers, inks, adhesives and coatings is not considered of concern for occupational exposure (inhalation and skin contact).

    Consumers

    Conclusion (iii) There is a need for limiting the risks; risk reduction measures which are already being applied shall be taken into account.

    This conclusion applies in case DIDP should be used as a substitute for other phthalates in toys because of concerns for hepatic toxicity as a consequence of repeated exposure of infants and newborn babies arising mainly by the oral route from mouthing and sucking toys and baby equipment.

    Pertaining to reduced offspring survival, due to the uncertainty related to the relevance of this endpoint for new-borns and infants and to the lack of experience in this particular field of trans- generational effect, no formal conclusion could be drawn.

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    The end products containing DIDP (clothes, building materials) and the sources of exposure (car and public transport interiors, food and food packaging) are unlikely to pose a risk for consumers (adults, infants and new-borns) following inhalation, skin contact and ingestion.

    Humans exposed via the environment

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    The indirect exposure via the environment is unlikely to pose a risk to humans following the main route of exposure, the oral route.

    Combined exposure

    Conclusion (iii) There is a need for limiting the risks; risk reduction measures which are already being applied shall be taken into account.

    This conclusion applies in case DIDP should be used as a substitute for other phthalates in toys because of concerns for hepatic toxicity as a consequence of repeated exposure of infants.

    Pertaining to reduced offspring survival, due to the uncertainty related to the relevance of this end point for infants and to the lack of experience in this particular field of trans-generational effect, no formal conclusion could be drawn.

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    As combined exposure of adults is almost exclusively related to occupational exposure, the overall assessment indicates no concern for adults. For infants, combined exposure, which is mainly related to exposure via the environment, is not considered of concern.

    Human health (risks from physico-chemical properties)

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    Concerning the effect assessment of DIDP, the properties of explosivity, flammability and oxidisation are not considered to pose a hazard.

    Source & ©: ECB "2003 Risk Assessment Report (RAR 041) on
    Di-"isodecyl" Phthalate (DIDP), Summary of the Report, Chapter 5: Results

    DINP

    RESULTS

    ENVIRONMENT

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    The production and use of DINP in PVC, other polymers, inks, adhesives, sealants and paints is unlikely to pose a risk to the environment. In addition, risks to the function of sewage treatment plants and the atmosphere are expected to be very low for both production and all uses.

    HUMAN HEALTH

    Human health (toxicity)

    Workers

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    The production and use of DINP in PVC, other polymers, inks, adhesives and coatings is not considered of concern for occupational exposure (inhalation and skin contact).

    Consumers

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    The end products containing DINP (clothes, building materials, toys and baby equipment) and the sources of exposure (car and public transport interiors, food and food packaging) are unlikely to pose a risk for consumers (adults, infants and newborns) following inhalation, skin contact and ingestion.

    Humans exposed via the environment

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    The indirect exposure via the environment is unlikely to pose a risk to humans following the main route of exposure, the oral route.

    Combined exposure

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    As combined exposure of adults is almost exclusively related to occupational exposure, the overall assessment indicates no concern for adults. For infants, combined exposure which is mainly related to exposure from toys and via the environment is not considered of concern.

    Human health (risks from physico-chemical properties)

    Conclusion (ii) There is at present no need for further information and/or testing and for risk reduction measures beyond those which are being applied already.

    Concerning the effect assessment of DINP, the properties of explosivity, flammability and oxidisation are not considered to pose a hazard.

    Source & ©: ECB "2003 Risk Assessment Report (RAR 046) on
    Di-"isodecyl" Phthalate (DIDP), Summary of the Report, Chapter 5: Results

    For more information, see the full ECB Risk Assessment Report:
     Chapter 5: Results

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